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Oxidative DNA damage is instrumental in hyperreplication stress-induced inviability of Escherichia coli

In Escherichia coli, an increase in the ATP bound form of the DnaA initiator protein results in hyperinitiation and inviability. Here, we show that such replication stress is tolerated during anaerobic growth. In hyperinitiating cells, a shift from anaerobic to aerobic growth resulted in appearance...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Charbon, Godefroid, Bjørn, Louise, Mendoza-Chamizo, Belén, Frimodt-Møller, Jakob, Løbner-Olesen, Anders
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245963/
https://ncbi.nlm.nih.gov/pubmed/25389264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1149
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