Energy Starvation Induces a Cell Cycle Arrest in Escherichia coli by Triggering Degradation of the DnaA Initiator Protein

During steady-state Escherichia coli growth, the amount and activity of the initiator protein, DnaA, controls chromosome replication tightly so that initiation only takes place once per origin in each cell cycle, regardless of growth conditions. However, little is known about the mechanisms involved...

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Publicat a:Front Mol Biosci
Autors principals: Charbon, Godefroid, Mendoza-Chamizo, Belén, Campion, Christopher, Li, Xiaobo, Jensen, Peter Ruhdal, Frimodt-Møller, Jakob, Løbner-Olesen, Anders
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Molecular Biosciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155583/
https://ncbi.nlm.nih.gov/pubmed/34055872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.629953
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