Energy Starvation Induces a Cell Cycle Arrest in Escherichia coli by Triggering Degradation of the DnaA Initiator Protein

During steady-state Escherichia coli growth, the amount and activity of the initiator protein, DnaA, controls chromosome replication tightly so that initiation only takes place once per origin in each cell cycle, regardless of growth conditions. However, little is known about the mechanisms involved...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Charbon, Godefroid, Mendoza-Chamizo, Belén, Campion, Christopher, Li, Xiaobo, Jensen, Peter Ruhdal, Frimodt-Møller, Jakob, Løbner-Olesen, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155583/
https://ncbi.nlm.nih.gov/pubmed/34055872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.629953
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