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Crystal structure of a DNA/Ba(2+) G-quadruplex containing a water-mediated C-tetrad

We have determined the 1.50 Å crystal structure of the DNA decamer, d(CCA(CNV)KGCGTGG) ((CNV)K, 3-cyanovinylcarbazole), which forms a G-quadruplex structure in the presence of Ba(2+). The structure contains several unique features including a bulged nucleotide and the first crystal structure observa...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Zhang, Diana, Huang, Terry, Lukeman, Philip S., Paukstelis, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245957/
https://ncbi.nlm.nih.gov/pubmed/25389267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1122
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