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Hug1 is an intrinsically disordered protein that inhibits ribonucleotide reductase activity by directly binding Rnr2 subunit

Rad53 is a conserved protein kinase with a central role in DNA damage response and nucleotide metabolism. We observed that the expression of a dominant-lethal form of RAD53 leads to significant expression changes for at least 16 genes, including the RNR3 and the HUG1 genes, both of which are involve...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nucleic Acids Res
Main Authors: Meurisse, Julie, Bacquin, Agathe, Richet, Nicolas, Charbonnier, Jean-Baptiste, Ochsenbein, Françoise, Peyroche, Anne
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245953/
https://ncbi.nlm.nih.gov/pubmed/25378334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1095
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