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Mapping the subunit interface of ribonucleotide reductase (RNR) using photo cross-linking

E. coli ribonucleotide reductase (RNR) catalyzes the conversion of nucleoside 5′-diphosphates to deoxynucleoside 5′-diphosphates and is a 1:1 complex of two homodimeric subunits: α2 and β2. As a first step towards mapping the subunit interface, β2 (V365C) was labeled with [(14)C]-benzophenone (BP) i...

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Bibliographic Details
Main Authors: Hassan, A Quamrul, Stubbe, JoAnne
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602823/
https://ncbi.nlm.nih.gov/pubmed/18762419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.08.048
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