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Time-resolved assembly of a nucleoprotein complex between Shigella flexneri virF promoter and its transcriptional repressor H-NS

The virF gene of Shigella, responsible for triggering the virulence cascade in this pathogenic bacterium, is transcriptionally repressed by the nucleoid-associated protein H-NS. The primary binding sites of H-NS within the promoter region of virF have been detected here by footprinting experiments i...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Ulissi, Ulisse, Fabbretti, Attilio, Sette, Marco, Giuliodori, Anna Maria, Spurio, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245942/
https://ncbi.nlm.nih.gov/pubmed/25389261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1052
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