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Small-Molecule Inhibitor of the Shigella flexneri Master Virulence Regulator VirF

VirF is an AraC family transcriptional activator that is required for the expression of virulence genes associated with invasion and cell-to-cell spread by Shigella flexneri, including multiple components of the type three secretion system (T3SS) machinery and effectors. We tested a small-molecule c...

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Detalhes bibliográficos
Main Authors: Koppolu, Veerendra, Osaka, Ichie, Skredenske, Jeff M., Kettle, Bria, Hefty, P. Scott, Li, Jiaqin, Egan, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811841/
https://ncbi.nlm.nih.gov/pubmed/24002059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00919-13
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