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Small-Molecule Inhibitor of the Shigella flexneri Master Virulence Regulator VirF

VirF is an AraC family transcriptional activator that is required for the expression of virulence genes associated with invasion and cell-to-cell spread by Shigella flexneri, including multiple components of the type three secretion system (T3SS) machinery and effectors. We tested a small-molecule c...

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Autores principales: Koppolu, Veerendra, Osaka, Ichie, Skredenske, Jeff M., Kettle, Bria, Hefty, P. Scott, Li, Jiaqin, Egan, Susan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811841/
https://ncbi.nlm.nih.gov/pubmed/24002059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00919-13
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