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Mechanism of Action and Initial, In Vitro SAR of an Inhibitor of the Shigella flexneri Virulence Regulator VirF

Shigella spp. are among the main causative agents of acute diarrheal illness and claim more than 1 million lives per year worldwide. There are multiple bacterial genes that control the pathogenesis of Shigella, but the virF gene may be the most important. This gene, located on the primary pathogenic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Emanuele, Anthony A., Garcia, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564171/
https://ncbi.nlm.nih.gov/pubmed/26352269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137410
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