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Timely binding of IHF and Fis to DARS2 regulates ATP–DnaA production and replication initiation
In Escherichia coli, the ATP-bound form of DnaA (ATP–DnaA) promotes replication initiation. During replication, the bound ATP is hydrolyzed to ADP to yield the ADP-bound form (ADP–DnaA), which is inactive for initiation. The chromosomal site DARS2 facilitates the regeneration of ATP–DnaA by catalyzi...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4245941/ https://ncbi.nlm.nih.gov/pubmed/25378325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1051 |
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