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Specific genomic sequences of E. coli promote replicational initiation by directly reactivating ADP-DnaA

In Escherichia coli, ATP-DnaA, unlike ADP-DnaA, can initiate chromosomal replication at oriC. The level of cellular ATP-DnaA fluctuates, peaking at around the time of replication initiation. However, it remains unknown how the ATP-DnaA level increases coordinately with the replication cycle. In this...

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Detalhes bibliográficos
Main Authors: Fujimitsu, Kazuyuki, Senriuchi, Takayuki, Katayama, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685538/
https://ncbi.nlm.nih.gov/pubmed/19401329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1775809
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