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Ribosomes in the balance: structural equilibrium ensures translational fidelity and proper gene expression

At equilibrium, empty ribosomes freely transit between the rotated and un-rotated states. In the cell, the binding of two translation elongation factors to the same general region of the ribosome stabilizes one state over the other. These stabilized states are resolved by expenditure of energy in th...

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Publicat a:Nucleic Acids Res
Autors principals: Musalgaonkar, Sharmishtha, Moomau, Christine A., Dinman, Jonathan D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245932/
https://ncbi.nlm.nih.gov/pubmed/25389262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1020
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