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Ribosomes in the balance: structural equilibrium ensures translational fidelity and proper gene expression

At equilibrium, empty ribosomes freely transit between the rotated and un-rotated states. In the cell, the binding of two translation elongation factors to the same general region of the ribosome stabilizes one state over the other. These stabilized states are resolved by expenditure of energy in th...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Musalgaonkar, Sharmishtha, Moomau, Christine A., Dinman, Jonathan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245932/
https://ncbi.nlm.nih.gov/pubmed/25389262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1020
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