Synthesis of a heparin-related GlcN–IdoA sulfation-site variable disaccharide library and analysis by Raman and ROA spectroscopy

Synthesis of an array of differentially sulfated GlcN–IdoA disaccharides, accessible on good scale, directly from l-iduronate components is described. These are specifically directed to provide the sulfation variability at the key most common biologically relevant sulfation-variable l-IdoA O-2 and d...

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Pubblicato in:Carbohydr Res
Autori principali: Miller, Gavin J., Hansen, Steen U., Baráth, Marek, Johannessen, Christian, Blanch, Ewan W., Jayson, Gordon C., Gardiner, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245711/
https://ncbi.nlm.nih.gov/pubmed/25457609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2014.06.026
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