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Simplifying complexity: genetically resculpting glycosphingolipid synthesis pathways in mice to reveal function

Glycosphingolipids (GSLs) are a group of plasma-membrane lipids notable for their extremely diverse glycan head groups. The metabolic pathways for GSLs, including the identity of the biosynthetic enzymes needed for synthesis of their glycans, are now well understood. Many of their cellular functions...

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Publicado en:Glycoconj J
Autores principales: Allende, Maria Laura, Proia, Richard L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245496/
https://ncbi.nlm.nih.gov/pubmed/25351657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-014-9563-5
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