Interruption of Glycosphingolipid Synthesis Enhances Osteoarthritis Development in Mice

OBJECTIVE: Glycosphingolipids (GSLs) are ubiquitous membrane components that modulate transmembrane signaling and mediate cell-to-cell and cell-to-matrix interactions. GSL expression is decreased in the articular cartilage of humans with osteoarthritis (OA). The aim of this study was to determine th...

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Detalhes bibliográficos
Main Authors: Seito, Naoki, Yamashita, Tadashi, Tsukuda, Yukinori, Matsui, Yuichiro, Urita, Atsushi, Onodera, Tomohiro, Mizutani, Takeomi, Haga, Hisashi, Fujitani, Naoki, Shinohara, Yasuro, Minami, Akio, Iwasaki, Norimasa
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382033/
https://ncbi.nlm.nih.gov/pubmed/22391889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34463
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