Polygenic overlap between kidney function and large artery atherosclerotic stroke

BACKGROUND AND PURPOSE: Epidemiological studies show strong associations between kidney dysfunction and risk of ischaemic stroke, the mechanisms of which are incompletely understood. We investigated whether these associations may reflect shared heritability due to a common polygenic basis and whethe...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Holliday, Elizabeth G., Traylor, Matthew, Malik, Rainer, Bevan, Stephen, Maguire, Jane, Koblar, Simon A., Sturm, Jonathan, Hankey, Graeme J., Oldmeadow, Christopher, McEvoy, Mark, Sudlow, Cathie, Rothwell, Peter M., Coresh, Josef, Hamet, Pavel, Tremblay, Johanne, Turner, Stephen T., de Andrade, Mariza, Rao, Madhumathi, Schmidt, Reinhold, Crick, Peter A., Robino, Antonietta, Peralta, Carmen A., Jukema, J. Wouter, Mitchell, Paul, Rosas, Sylvia E., Wang, Jie Jin, Scott, Rodney J., Dichgans, Martin, Mitchell, Braxton D., Linda Kao, W. H., Fox, Caroline S., Levi, Christopher, Attia, John, Markus, Hugh S
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245455/
https://ncbi.nlm.nih.gov/pubmed/25352485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.006609
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