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Bortezomib sensitizes non-small cell lung cancer to mesenchymal stromal cell-delivered inducible caspase-9-mediated cytotoxicity

Delivery of suicide genes to solid tumors represents a promising tumor therapy strategy. However, slow or limited killing by suicide genes and ineffective targeting of the tumor has reduced effectiveness. We have adapted a suicide system based on an inducible caspase-9 (iC9) protein that is activate...

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Vydáno v:Cancer Gene Ther
Hlavní autoři: Ando, Miki, Hoyos, Valentina, Yagyu, Shigeki, Tao, Wade, Ramos, Carlos A., Dotti, Gianpietro, Brenner, Malcolm K., Bouchier-Hayes, Lisa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245333/
https://ncbi.nlm.nih.gov/pubmed/25323693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2014.53
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