Identification of Small Molecule Modulators of Gene Transcription with Anticancer Activity

[Image: see text] Epigenetic regulation of gene expression is essential in many biological processes, and its deregulation contributes to pathology including tumor formation. We used an image-based cell assay that measures the induction of a silenced GFP-estrogen receptor reporter to identify novel...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Tran, Tram Anh, Wichterman-Kouznetsova, Jennifer, Varghese, Diana, Huang, Ruili, Huang, Wenwei, Becker, Matthias, Austin, Christopher P., Inglese, James, Johnson, Ronald L., Martinez, Elisabeth D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245161/
https://ncbi.nlm.nih.gov/pubmed/25188650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500532x
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