Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells.

We report that transfusions of RT1u Wistar-Furth (WF) spleen cells prevented spontaneous diabetes in the RT1u BB/W rat while RT1b Buffalo rat spleen cells did not. In addition, donor origin WF T lymphocytes were detected in nondiabetic-susceptible BB/W recipients 5 mo after transfusion. Survival of...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Rossini, A A, Mordes, J P, Greiner, D L, Nakano, K, Appel, M C, Handler, E S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3958191/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112448
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