Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells.

We report that transfusions of RT1u Wistar-Furth (WF) spleen cells prevented spontaneous diabetes in the RT1u BB/W rat while RT1b Buffalo rat spleen cells did not. In addition, donor origin WF T lymphocytes were detected in nondiabetic-susceptible BB/W recipients 5 mo after transfusion. Survival of...

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Main Authors: Rossini, A A, Mordes, J P, Greiner, D L, Nakano, K, Appel, M C, Handler, E S
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC424507/
https://ncbi.nlm.nih.gov/pubmed/3958191
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