Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat.

The abnormalities underlying diabetic neuropathy appear to be multiple and involve metabolic neuronal and vasomediated defects. The accumulation of long-chain fatty acids and impaired beta-oxidation due to deficiencies in carnitine and/or its esterified derivatives, such as acetyl-L-carnitine, may h...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Sima, A A, Ristic, H, Merry, A, Kamijo, M, Lattimer, S A, Stevens, M J, Greene, D A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8621774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118621
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