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Absence of ALOX5 gene prevents stress-induced memory deficits, synaptic dysfunction and tauopathy in a mouse model of Alzheimer's disease

Although the initial events of Alzheimer's disease (AD) are still not known, it is clear that the disease in its sporadic form results from the combination of genetic and environmental risk factors. Among the latter, behavioral stress has been increasingly recognized as an important factor in t...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Joshi, Yash B., Giannopoulos, Phillip F., Chu, Jin, Sperow, Margaret, Kirby, Lynn G., Abood, Mary E., Praticò, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245048/
https://ncbi.nlm.nih.gov/pubmed/25122659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu412
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