טוען...
Pharmacologic inhibition of 5Lipoxygenase improves memory, rescues synaptic dysfunction and ameliorates tau pathology in a transgenic model of tauopathy
BACKGROUND: The 5-lipoxygenase (5LO) is a protein widely distributed in the central nervous system where modulates amyloidosis and memory impairments in transgenic mouse models of Alzheimer’s disease. However, no data are available as to whether 5LO is elevated in human tauopathy, or if it directly...
שמור ב:
| הוצא לאור ב: | Biol Psychiatry |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529386/ https://ncbi.nlm.nih.gov/pubmed/25802082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.01.015 |
| תגים: |
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