Incubation of MDCO-216 (ApoA-IMilano/POPC) with Human Serum Potentiates ABCA1-Mediated Cholesterol Efflux Capacity, Generates New Prebeta-1 HDL, and Causes an Increase in HDL Size

Eitemau Tebyg

• Incubation of MDCO-216 (ApoA-IMilano/POPC) with Human Serum Potentiates ABCA1-Mediated Cholesterol Efflux Capacity, Generates New Prebeta-1 HDL, and Causes an Increase in HDL Size
  gan: Herman J. Kempen, et al.
  Cyhoeddwyd: (2014-01-01)
• A single infusion of MDCO-216 (ApoA-1 Milano/POPC) increases ABCA1-mediated cholesterol efflux and pre-beta 1 HDL in healthy volunteers and patients with stable coronary artery disease
  gan: Kallend, D.G., et al.
  Cyhoeddwyd: (2016)
• Effect of repeated apoA-IMilano/POPC infusion on lipids, (apo)lipoproteins, and serum cholesterol efflux capacity in cynomolgus monkeys
  gan: Kempen, Herman J., et al.
  Cyhoeddwyd: (2013)
• MDCO-216 Does Not Induce Adverse Immunostimulation, in Contrast to Its Predecessor ETC-216
  gan: Reijers, Joannes A. A., et al.
  Cyhoeddwyd: (2017)
• ApoA-IV promotes the biogenesis of apoA-IV-containing HDL particles with the participation of ABCA1 and LCAT
  gan: Duka, Adelina, et al.
  Cyhoeddwyd: (2013)