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Reconstitution of the augmin complex provides insights into its architecture and function
Proper microtubule nucleation during cell division requires augmin, a microtubule-associated hetero-octameric protein complex. In current models, augmin recruits γ-tubulin, via its hDgt6 subunit’s C-terminus, to nucleate microtubules within spindles. However, augmin’s biochemical complexity has rest...
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| Publicado no: | Nat Cell Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244909/ https://ncbi.nlm.nih.gov/pubmed/25173975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3030 |
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