myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course.

44 small cell lung cancer cell lines established from 227 patients were studied for myc family DNA amplification (c-myc, N-myc, and L-myc). Two of 19 lines (11%) established from untreated patients' tumors had DNA amplification (one N-myc and one L-myc), compared with 11 of 25 (5 c-myc, 3 N-myc...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Johnson, B E, Ihde, D C, Makuch, R W, Gazdar, A F, Carney, D N, Oie, H, Russell, E, Nau, M M, Minna, J D
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1987
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3034978/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112999
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