myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course.

44 small cell lung cancer cell lines established from 227 patients were studied for myc family DNA amplification (c-myc, N-myc, and L-myc). Two of 19 lines (11%) established from untreated patients' tumors had DNA amplification (one N-myc and one L-myc), compared with 11 of 25 (5 c-myc, 3 N-myc...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Johnson, B E, Ihde, D C, Makuch, R W, Gazdar, A F, Carney, D N, Oie, H, Russell, E, Nau, M M, Minna, J D
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 1987
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3034978/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112999
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