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myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course.

44 small cell lung cancer cell lines established from 227 patients were studied for myc family DNA amplification (c-myc, N-myc, and L-myc). Two of 19 lines (11%) established from untreated patients' tumors had DNA amplification (one N-myc and one L-myc), compared with 11 of 25 (5 c-myc, 3 N-myc...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Johnson, B E, Ihde, D C, Makuch, R W, Gazdar, A F, Carney, D N, Oie, H, Russell, E, Nau, M M, Minna, J D
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1987
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3034978/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112999
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