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Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution

[Image: see text] Genetically encoded fluorescent ribonucleic acids (RNAs) have diverse applications, including imaging RNA trafficking and as a component of RNA-based sensors that exhibit fluorescence upon binding small molecules in live cells. These RNAs include the Spinach and Spinach2 aptamers,...

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Publicat a:J Am Chem Soc
Autors principals: Filonov, Grigory S., Moon, Jared D., Svensen, Nina, Jaffrey, Samie R.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244833/
https://ncbi.nlm.nih.gov/pubmed/25337688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508478x
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