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Endocannabinoids Anandamide and 2-Arachidonoylglycerol Are Substrates for Human CYP2J2 Epoxygenase

The endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are arachidonic acid (AA) derivatives that are known to regulate human cardiovascular functions. CYP2J2 is the primary cytochrome P450 in the human heart and is most well known for the metabolism of AA to the biologically acti...

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Detaylı Bibliyografya
Yayımlandı:J Pharmacol Exp Ther
Asıl Yazarlar: McDougle, Daniel R., Kambalyal, Amogh, Meling, Daryl D., Das, Aditi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244587/
https://ncbi.nlm.nih.gov/pubmed/25277139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.216598
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