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Endocannabinoids Anandamide and 2-Arachidonoylglycerol Are Substrates for Human CYP2J2 Epoxygenase

The endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are arachidonic acid (AA) derivatives that are known to regulate human cardiovascular functions. CYP2J2 is the primary cytochrome P450 in the human heart and is most well known for the metabolism of AA to the biologically acti...

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書目詳細資料
發表在:J Pharmacol Exp Ther
Main Authors: McDougle, Daniel R., Kambalyal, Amogh, Meling, Daryl D., Das, Aditi
格式: Artigo
語言:Inglês
出版: The American Society for Pharmacology and Experimental Therapeutics 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244587/
https://ncbi.nlm.nih.gov/pubmed/25277139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.216598
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