Role of CYP1A1 in Modulating the Vascular and Blood Pressure Benefits of Omega-3 Polyunsaturated Fatty Acids

The mechanisms that mediate the cardiovascular protective effects of omega 3 (n-3) polyunsaturated fatty acids (PUFAs) have not been fully elucidated. Cytochrome P450 1A1 efficiently metabolizes n-3 PUFAs to potent vasodilators. Thus, we hypothesized that dietary n-3 PUFAs increase nitric oxide (NO)...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Agbor, Larry N., Wiest, Elani F., Rothe, Michael, Schunck, Wolf-Hagen, Walker, Mary K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2014
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244579/
https://ncbi.nlm.nih.gov/pubmed/25316121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.219535
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