Possible Role of CYP450 Generated Omega-3/Omega-6 PUFA Metabolites in the Modulation of Blood Pressure and Vascular Function in Obese Children

Obesity is often accompanied by metabolic and haemodynamic disorders such as hypertension, even during childhood. Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP450) enzymes to epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE), vasoactive and natriuretic met...

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Veröffentlicht in:Nutrients
Hauptverfasser: Bonafini, Sara, Giontella, Alice, Tagetti, Angela, Marcon, Denise, Montagnana, Martina, Benati, Marco, Gaudino, Rossella, Cavarzere, Paolo, Karber, Mirjam, Rothe, Michael, Minuz, Pietro, Antoniazzi, Franco, Maffeis, Claudio, Schunck, Wolf Hagen, Fava, Cristiano
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267577/
https://ncbi.nlm.nih.gov/pubmed/30400671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10111689
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