Possible Role of CYP450 Generated Omega-3/Omega-6 PUFA Metabolites in the Modulation of Blood Pressure and Vascular Function in Obese Children

Obesity is often accompanied by metabolic and haemodynamic disorders such as hypertension, even during childhood. Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP450) enzymes to epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE), vasoactive and natriuretic met...

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Vydáno v:Nutrients
Hlavní autoři: Bonafini, Sara, Giontella, Alice, Tagetti, Angela, Marcon, Denise, Montagnana, Martina, Benati, Marco, Gaudino, Rossella, Cavarzere, Paolo, Karber, Mirjam, Rothe, Michael, Minuz, Pietro, Antoniazzi, Franco, Maffeis, Claudio, Schunck, Wolf Hagen, Fava, Cristiano
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267577/
https://ncbi.nlm.nih.gov/pubmed/30400671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10111689
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