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Proton-Mediated Block of Ca(2+) Channels during Multivesicular Release Regulates Short-Term Plasticity at an Auditory Hair Cell Synapse
Synaptic vesicles release both neurotransmitter and protons during exocytosis, which may result in a transient acidification of the synaptic cleft that can block Ca(2+) channels located close to the sites of exocytosis. Evidence for this effect has been reported for retinal ribbon-type synapses, but...
Enregistré dans:
| Publié dans: | J Neurosci |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244462/ https://ncbi.nlm.nih.gov/pubmed/25429130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2304-14.2014 |
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