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Proton-Mediated Block of Ca(2+) Channels during Multivesicular Release Regulates Short-Term Plasticity at an Auditory Hair Cell Synapse

Synaptic vesicles release both neurotransmitter and protons during exocytosis, which may result in a transient acidification of the synaptic cleft that can block Ca(2+) channels located close to the sites of exocytosis. Evidence for this effect has been reported for retinal ribbon-type synapses, but...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cho, Soyoun, von Gersdorff, Henrique
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244462/
https://ncbi.nlm.nih.gov/pubmed/25429130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2304-14.2014
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