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Clustered Ca(2+) Channels Are Blocked by Synaptic Vesicle Proton Release at Mammalian Auditory Ribbon Synapses

A Ca(2+) current transient block (I(Ca)TB) by protons occurs at some ribbon-type synapses after exocytosis, but this has not been observed at mammalian hair cells. Here we show that a robust I(Ca)TB occurs at post-hearing mouse and gerbil inner hair cell (IHC) synapses, but not in immature IHC synap...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Vincent, Philippe F.Y., Cho, Soyoun, Tertrais, Margot, Bouleau, Yohan, von Gersdorff, Henrique, Dulon, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365105/
https://ncbi.nlm.nih.gov/pubmed/30566869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.11.072
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