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Mature MiRNAs Form Secondary Structure, which Suggests Their Function beyond RISC
The generally accepted model of the miRNA-guided RNA down-regulation suggests that mature miRNA targets mRNA in a nucleotide sequence-specific manner. However, we have shown that the nucleotide sequence of miRNA is not the only determinant of miRNA specificity. Using specific nucleases, T1, V1 and S...
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| 發表在: | PLoS One |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244182/ https://ncbi.nlm.nih.gov/pubmed/25423301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113848 |
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