Mature MiRNAs Form Secondary Structure, which Suggests Their Function beyond RISC

The generally accepted model of the miRNA-guided RNA down-regulation suggests that mature miRNA targets mRNA in a nucleotide sequence-specific manner. However, we have shown that the nucleotide sequence of miRNA is not the only determinant of miRNA specificity. Using specific nucleases, T1, V1 and S...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Belter, Agnieszka, Gudanis, Dorota, Rolle, Katarzyna, Piwecka, Monika, Gdaniec, Zofia, Naskręt-Barciszewska, Mirosława Z., Barciszewski, Jan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244182/
https://ncbi.nlm.nih.gov/pubmed/25423301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113848
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