Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum

The molecular pathogenesis of autism is complex and involves numerous genomic, epigenomic, proteomic, metabolic, and physiological alterations. Elucidating and understanding the molecular processes underlying the pathogenesis of autism is critical for effective clinical management and prevention of...

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Veröffentlicht in:PLoS One
Hauptverfasser: Shpyleva, Svitlana, Ivanovsky, Samuil, de Conti, Aline, Melnyk, Stepan, Tryndyak, Volodymyr, Beland, Frederick A., James, S. Jill, Pogribny, Igor P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244134/
https://ncbi.nlm.nih.gov/pubmed/25423485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113712
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