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Cdk5 phosphorylation of EFhd2 at S74 affects its calcium binding activity

EFhd2 is a calcium binding protein, which is highly expressed in the central nervous system and associated with pathological forms of tau proteins in tauopathies. Previous phosphoproteomics studies and bioinformatics analysis suggest that EFhd2 may be phosphorylated. Here, we determine whether Cdk5,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Protein Sci
Hauptverfasser: Vázquez-Rosa, Edwin, Rodríguez-Cruz, Eva N, Serrano, Sybelle, Rodríguez-Laureano, Lucelenie, Vega, Irving E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243992/
https://ncbi.nlm.nih.gov/pubmed/24917152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2499
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