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Cdk5 phosphorylation of EFhd2 at S74 affects its calcium binding activity

EFhd2 is a calcium binding protein, which is highly expressed in the central nervous system and associated with pathological forms of tau proteins in tauopathies. Previous phosphoproteomics studies and bioinformatics analysis suggest that EFhd2 may be phosphorylated. Here, we determine whether Cdk5,...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Vázquez-Rosa, Edwin, Rodríguez-Cruz, Eva N, Serrano, Sybelle, Rodríguez-Laureano, Lucelenie, Vega, Irving E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243992/
https://ncbi.nlm.nih.gov/pubmed/24917152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2499
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