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The Calcium-Binding Protein EFhd2 Modulates Synapse Formation In Vitro and Is Linked to Human Dementia

EFhd2 is a calcium-binding adaptor protein that has been found to be associated with pathologically aggregated tau in the brain in Alzheimer disease and in a mouse model of frontotemporal dementia. EFhd2 has cell type–specific functions, including the modulation of intracellular calcium responses, a...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Borger, Eva, Herrmann, Abigail, Mann, David A., Spires-Jones, Tara, Gunn-Moore, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Association of Neuropathologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238966/
https://ncbi.nlm.nih.gov/pubmed/25383639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000138
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