In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives

BACKGROUND AND PURPOSE: An innovative chemical approach, named peptide welding technology (PWT), allows the synthesis of multibranched peptides with extraordinary high yield, purity and reproducibility. With this approach, three different tetrabranched derivatives of nociceptin/orphanin FQ (N/OFQ) h...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Rizzi, A, Malfacini, D, Cerlesi, M C, Ruzza, C, Marzola, E, Bird, M F, Rowbotham, D J, Salvadori, S, Guerrini, R, Lambert, D G, Calo, G
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243985/
https://ncbi.nlm.nih.gov/pubmed/24903280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12799
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