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The membrane protein Pannexin1 forms two open channel conformations depending on the mode of activation

Pannexin1 (Panx1) participates in several signaling events that involve ATP release, including the innate immune response, ciliary beat in airway epithelia and oxygen supply in the vasculature. The view that Panx1 forms a large ATP-release channel has been challenged by the association of a low cond...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Wang, Junjie, Ambrosi, Cinzia, Qiu, Feng, Jackson, David G., Sosinsky, Gina, Dahl, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243966/
https://ncbi.nlm.nih.gov/pubmed/25056878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005431
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