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New mechanism for glomerular injury. Myeloperoxidase-hydrogen peroxide-halide system.
Reactive oxygen species, particularly hydrogen peroxide (H2O2), participate in neutrophil-mediated glomerulonephritis. However, the mechanism of H2O2 neptrotoxicity is unknown. Myeloperoxidase (MPO), a neutrophil cationic enzyme that localizes in glomeruli, can react with H2O2 and halides to form hi...
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| Publicado en: | J Clin Invest |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1987
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3033023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112965 |
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