New mechanism for glomerular injury. Myeloperoxidase-hydrogen peroxide-halide system.

Reactive oxygen species, particularly hydrogen peroxide (H2O2), participate in neutrophil-mediated glomerulonephritis. However, the mechanism of H2O2 neptrotoxicity is unknown. Myeloperoxidase (MPO), a neutrophil cationic enzyme that localizes in glomeruli, can react with H2O2 and halides to form hi...

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Bibliografiske detaljer
Main Authors: Johnson, R J, Couser, W G, Chi, E Y, Adler, S, Klebanoff, S J
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC424393/
https://ncbi.nlm.nih.gov/pubmed/3033023
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