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Menthol enhances phasic and tonic GABA(A) receptor-mediated currents in midbrain periaqueductal grey neurons

BACKGROUND AND PURPOSE: Menthol, a naturally occurring compound in the essential oil of mint leaves, is used for its medicinal, sensory and fragrant properties. Menthol acts via transient receptor potential (TRPM8 and TRPA1) channels and as a positive allosteric modulator of recombinant GABA(A) rece...

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Publicat a:Br J Pharmacol
Autors principals: Lau, Benjamin K, Karim, Shafinaz, Goodchild, Ann K, Vaughan, Christopher W, Drew, Geoffrey M
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243856/
https://ncbi.nlm.nih.gov/pubmed/24460753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12602
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