Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey

BACKGROUND AND PURPOSE: Endogenous cannabinoids (endocannabinoids) in the periaqueductal grey (PAG) play a vital role in mediating stress-induced analgesia. This analgesic effect of endocannabinoids is enhanced by pharmacological inhibition of their degradative enzymes. However, the specific effects...

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Библиографические подробности
Опубликовано в: :Br J Pharmacol
Главные авторы: Lau, Benjamin K, Drew, Geoffrey M, Mitchell, Vanessa A, Vaughan, Christopher W
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2014
Предметы:
Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294036/
https://ncbi.nlm.nih.gov/pubmed/25041240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12839
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