Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent

Following biosynthesis, both GLUT1 and VSV-G proteins appear rapidly (2–3 h) at the plasma membrane, whereas GLUT4 is retained in intracellular membrane compartments and does not display any significant insulin responsiveness until 6–9 h. Surprisingly, the acquisition of insulin responsiveness did n...

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Détails bibliographiques
Auteurs principaux: Watson, Robert T, Khan, Ahmir H, Furukawa, Megumi, Hou, June Chunqiu, Li, Lin, Kanzaki, Makoto, Okada, Shuichi, Kandror, Konstantin V, Pessin, Jeffrey E
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC424358/
https://ncbi.nlm.nih.gov/pubmed/15116067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600159
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