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Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent

Following biosynthesis, both GLUT1 and VSV-G proteins appear rapidly (2–3 h) at the plasma membrane, whereas GLUT4 is retained in intracellular membrane compartments and does not display any significant insulin responsiveness until 6–9 h. Surprisingly, the acquisition of insulin responsiveness did n...

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Published in:EMBO J
Main Authors: Watson, Robert T, Khan, Ahmir H, Furukawa, Megumi, Hou, June Chunqiu, Li, Lin, Kanzaki, Makoto, Okada, Shuichi, Kandror, Konstantin V, Pessin, Jeffrey E
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2004
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Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15116067/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600159
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