Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent

Following biosynthesis, both GLUT1 and VSV-G proteins appear rapidly (2–3 h) at the plasma membrane, whereas GLUT4 is retained in intracellular membrane compartments and does not display any significant insulin responsiveness until 6–9 h. Surprisingly, the acquisition of insulin responsiveness did n...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Watson, Robert T, Khan, Ahmir H, Furukawa, Megumi, Hou, June Chunqiu, Li, Lin, Kanzaki, Makoto, Okada, Shuichi, Kandror, Konstantin V, Pessin, Jeffrey E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15116067/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600159
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